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How it works: Kisspeptin signals your brain to release GnRH (gonadotropin-releasing hormone), which triggers a cascade: your pituitary releases LH and FSH, which stimulate your reproductive organs

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Besides the acute phase gastrointestinal effects which may lead to up to 10% of people discontinuing the drugs, there are other potential GI side effects of obstruction, excessive loss of muscle mass, and potentially association with some eye disease adverse events