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Recent studies also show that β-sitosterol suppresses pro-survival signaling cascades—for instance, an oxidized β-sitosterol derivative significantly downregulated phosphorylated ERK1/2 and NF-κB p65 levels, leading to increased ceramide accumulation and apoptosis in breast and liver cancer cells (97)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Dawson H, Solano-Aguilar G, Beal M, et al