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A 2023 narrative review in the Anais Brasileiros de Dermatologia comparing adolescent and adult acne across epidemiology, pathophysiology, and treatment confirms that adult-onset acne is driven by a different hormonal mechanism than adolescent acne and requires modified treatment approaches, particularly regarding retinoid selection and barrier preservation

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Functions of vitamin B12 and folate Vitamin B12 (cobalamin) and folate (vitamin B9) are vitamins that serve important functions in the human body