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Pavilion notes

Duotone board — mint brief on the left, coral-folded detail sheet on the right.

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Unlike PD-L1, which is often induced as part of adaptive resistance within the tumour microenvironment, many other checkpoint pathways involve ligands that are broadly expressed in normal tissues, potentially narrowing their therapeutic windows

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Diabetes is also strongly associated with PAD, with the strongest associations seen in patients with long-standing and uncontrolled diabetes [2]

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