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The animal studies show that supplementation of l-carnitine elevates plasma IGF-1 concentration, despite various doses consumed daily: from ~1 mg/kg body weight in sows [50], to ~100 mg/kg body weight in rats [22]

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Comparable efficacy in clinical trials, minimal side effects, and lower monthly costs suggest that ALA and ALC should be considered among the accepted first-line treatment options for neuropathic pain