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These cells are responsible for producing and maintaining the myelin sheath of nerve cells so the GLP-1R agonists, like NLY01, would target mature oligodendrocytes

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TMG should not be part of the initial protocol and should only be added after escalating doses of Methyl-B12 fail, if Methyl-B12 produces “intolerable” side effects according to the definitions given above, or if Methyl-B12 produces no significant benefits