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Functional Status and Associated Codes Z15.01–Z15.09 : Genetic susceptibility to malignant neoplasm (BRCA1/BRCA2, Lynch syndrome) — for patients with confirmed genetic predisposition without current malignancy Z80.xx : Family history of malignant neoplasm — code for family history screening Z17.0 / Z17.1 : Estrogen receptor positive / negative status — document for breast/gynecologic cancers R97.x : Elevated tumor markers without confirmed malignancy (R97.0 AFP, R97.1 CEA, R97.20 PSA elevated, R97.21 rising PSA post-prostatectomy) E34.0 : Carcinoid syndrome (functional tumors C7A.x) D37–D48 : Neoplasms of uncertain behavior — use when pathology cannot confirm malignant vs benign 🔢 ICD-10-CM Code Set (FY2026) Active Malignancy — Selected Primary Sites Hematologic Malignancies Metastatic / Secondary Sites (C77–C79) Personal History of Malignancy (Z85.x) — Treatment Complete, NED Supporting / Associated Codes 🛡️ Audit Alert — Z85.x vs Active C-Code Assigning Z85.x when the patient still receives adjuvant chemotherapy, radiation, or immunotherapy is a critical coding error

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