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In the case of berberine hydrochloride, synthetic production (i.e., using synthetic precursors and not plant material) offers several practical advantages, specifically, higher yields [17] and therefore lower production costs, which make it attractive for meeting rising global demand

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As of now, the body of literature is focused on the specific metabolic parameters of diet-induced obesity in mice, leaving a wide gap between these findings and any potential application in broader, non-obese, or human-specific contexts [2]