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Conversely, the exportin-1 inhibitor selixenor in combination with doxorubicin achieved 3 PR and 4 SD in nine patients with unresectable or metastatic MPNST, while one patient with NF1-associated MPNST obtained a disease stabilization after selinexor alone, lasting 13.5 months [200]

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10.1097/coc.0000000000000303 15