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BPC 157 has beneficial effects on inflammation, hemorrhage, and edema after traumatic brain injury [33], various severe encephalopathies (which follow gastrointestinal and/or liver lesions), NSAID overdose [34–37], or insulin overdose seizures [38] and on severe muscle weakness after exposure to the specific neurotoxin cuprizone in a rat multiple sclerosis model [39] or magnesium overdose [40]

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Clinical Trials of IN Administration of Peptides for CNS Therapy Although N-to-B delivery has been well established in clinical trials, improved N-to-B delivery systems have yet to be associated with approved products [6]