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Molecular Basis of Nitrosamine Formation Nitrosamines are a class of chemical compounds characterized by the presence of a nitroso group (–N=O) bonded to a nitrogen atom, typically of a secondary or tertiary amine (general structure: R 1 N(–R 2 )–N=O)

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Absolute quantitation of NAPQI-modified rat serum albumin by LC-MS/MS: monitoring acetaminophen covalent binding in vivo